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- Title
Vitamin E and the Risk of Prostate Cancer.
- Authors
Klein, Eric A.; Thompson Jr., Ian M.; Tangen, Catherine M.; Crowley, John J.; Lucia, M. Scott; Goodman, Phyllis J.; Minasian, Lori M.; Ford, Leslie G.; Parnes, Howard L.; Gaziano, J. Michael; Karp, Daniel D.; Lieber, Michael M.; Walther, Philip J.; Klotz, Laurence; Parsons, J. Kellogg; Chin, Joseph L.; Darke, Amy K.; Lippman, Scott M.; Goodman, Gary E.; Meyskens Jr., Frank L.
- Abstract
The article discusses a study which determined the long-term effect of vitamin E and selenium on risk of prostate cancer in relatively healthy men. Statistical analysis showed the significant increase in the risk of prostate cancer among healthy men who received vitamin E dietary supplements. According to data, 620 men in the vitamin E group and 575 men in the selenium group developed prostate cancer, compared with 529 men in the placebo group. Data indicate the frequency of use of prostate-specific antigen (PSA) and digital rectal examination, as well as the rate of prostate cancer detection in all the treatment groups.
- Subjects
VITAMIN E; SELENIUM; PROSTATE cancer risk factors; MALE reproductive organ diseases; PROSTATE-specific antigen; CANCER in men; DIAGNOSIS
- Publication
JAMA: Journal of the American Medical Association, 2011, Vol 306, Issue 14, p1549
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2011.1437