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- Title
Acid-Suppressive Medication Use and the Risk for Hospital-Acquired Pneumonia.
- Authors
Herzig, Shoshana J.; Howell, Michael D.; Long H. Ngo; Marcantonio, Edward R.
- Abstract
The article presents research examining the possible association between acid-suppressive medication and hospital-acquired pneumonia. The design of the cohort study involving patients of at least 18 years of age who were admitted to a large, urban, academic medical center for 3 or more days is described. The outcomes measured include the incidence of hospital-acquired pneumonia in patients exposed and unexposed to acid-suppressive medication. Results indicated that acid-suppressive medication use was associated with a 30% increase in the risk of contracting pneumonia in a hospital setting. However, statistically significant risk was only demonstrated for proton-pump inhibitor use.
- Subjects
ANTACIDS; NOSOCOMIAL infections; PNEUMONIA; PROTON pump inhibitors; ACID neutralizing capacity; HOSPITAL patients; HOSPITAL care; DISEASES; INFECTIOUS disease transmission
- Publication
JAMA: Journal of the American Medical Association, 2009, Vol 301, Issue 20, p2120
- ISSN
0098-7484
- Publication type
Article
- DOI
10.1001/jama.2009.722