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- Title
In vitro Study: Efficacy of Artemisia monosperma Leaves Extract on Eimeria papillata.
- Authors
Maodaa, Saleh N.; Al-Shaebi, Esam M.; Abdel-Gaber, Rewaida; Alatawi, Afaf; Alawwad, Sarah A.; Al-Quraishy, Saleh
- Abstract
Background: Traditional medicine has long utilized medicinal plants that contain a rich source of biologically active phytochemicals. Many of these have antioxidant and anti-inflammatory properties, which can reduce the risk of many diseases. Numerous animals are afflicted by the disease coccidiosis, which causes significant economic losses. Drug abuse and overuse have led to the emergence of drug-resistant strains of Eimeria spp. Methods: In this study, Artemisia monosperma leaf methanolic extract (AMLE) was prepared and tested in vitro as an anticoccidial using the oocyst of Eimeria papillata. Result: Fifteen different functional groups were present in AMLE using infrared spectroscopy. Also, quantitative results showed phenolics and flavonoids 39.7±0.3 and 33.4±0.2 (mg TAE/g DW) respectively in AMLE. Moreover, at 96 h, significant inhibition of process sporulation for E. papillata oocyst was observed when exposed to AMLE (300 mg/mL) and formalin 5%, while amprolium, DettolTM and phenol showed different levels of inhibition. Our results showed that AMLE has anticoccidial activity, which promotes the conduct of numerous in vivo research to discover an efficient treatment.
- Subjects
EIMERIA; ARTEMISIA; IN vitro studies; INFRARED spectroscopy; DRUG abuse
- Publication
Indian Journal of Animal Research, 2024, Vol 58, Issue 2, p225
- ISSN
0367-6722
- Publication type
Article
- DOI
10.18805/IJAR.BF-1696