We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Influence of anti‐inflammatory irrigant on substance P expression for single‐visit root canal treatment of teeth with irreversible pulpitis.
- Authors
Bamini, Lavanya; Anand Sherwood, I; Abbott, Paul V.; Uthandakalaipandian, Ramesh; Velu, Vijay
- Abstract
One of the main objectives of root canal treatment is to alleviate the pain associated with irreversibly inflamed pulps. However, some patients may have moderate to severe pain following treatment. The aim of this study was to compare and assess the effect of ketorolac tromethamine on substance P expression in the pulp and periapical tissues when used as a root canal irrigant for single‐visit root canal treatment in teeth with irreversible pulpitis. Thirty‐six patients were randomly allotted to three irrigant groups – saline (n = 14), 3% sodium hypochlorite (n = 11) and ketorolac tromethamine (n = 11). Pulp blood samples (S1) were collected on gaining access to the pulp, and periapical blood samples (S2) were collected after root canal preparation. Quantification of substance P was done by ELISA test. The ketorolac tromethamine group had greater reduction in substance P expression (S2). Post‐operative pain levels were not significantly influenced by the different root canal irrigants.
- Subjects
SUBSTANCE P; DENTAL pulp cavities; ROOT canal treatment; GUTTA-percha; DENTAL pulp capping; PAIN management; SODIUM hypochlorite
- Publication
Australian Endodontic Journal, 2020, Vol 46, Issue 1, p73
- ISSN
1329-1947
- Publication type
Article
- DOI
10.1111/aej.12353