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- Title
General and Direct Synthesis of Indolizine-1-carbaldehydes by 1,3-Dipolar Cycloaddition of Phenylpropiolaldehyde with Pyridinium Ylides.
- Authors
Gao, Tao; Chen, Xiuling; Jiang, Longqiang; Wu, Minghu; Guo, Haibing; Wang, Jian; Sun, Shaofa; Oiler, Jeremy; Xing, Yalan
- Abstract
An efficient and one-step synthesis of indolizine-1-carbaldehydes from phenylpropiolaldehyde and pyridinium ylides was developed. The elegant methodology afforded functionalized indolizines with easy operation under mild reaction conditions and with wide substrate scope.
- Subjects
RING formation (Chemistry); PYRIDINIUM compounds; HYDROGEN atom; HETEROARENES; COUPLING reactions (Chemistry)
- Publication
European Journal of Organic Chemistry, 2016, Vol 2016, Issue 29, p4957
- ISSN
1434-193X
- Publication type
Article
- DOI
10.1002/ejoc.201600945