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- Title
Impulse Oscillometry as an Alternative Lung Function Test for Hospitalized Adults.
- Authors
Kleinhendler, Eyal; Rosman, Maya; Fireman, Elisabeth; Freund, Ophir; Gershman, Ivgeny; Pumin, Irena; Perluk, Tal; Tiran, Boaz; Unterman, Avraham; Bar-Shai, Amir
- Abstract
BACKGROUND: Impulse oscillometry (IOS) is a noninvasive technique that measures lung physiology independently of patient effort. In the present study, we aimed to investigate the utility of IOS parameters in comparison with pulmonary function testing (PFT) among hospitalized subjects, with emphasis on obstructive and small airway diseases. METHODS: Sixty-one subjects hospitalized either with unexplained dyspnea or for pre-surgery evaluation were included in the study. All subjects underwent PFTs and IOS test. The correlation between IOS results and PFTs was examined in different subgroups. The ability of IOS parameters to predict abnormal PFTs was evaluated using the area under the receiver operating characteristic (ROC) curve, and optimal cutoff values were calculated. RESULTS: IOS results were found to correlate with PFT values. Subgroup analysis revealed that these correlations were higher in younger (age < 70) and non-obese (body mass index < 25kg/m²) subjects. The resonant frequency was an independent predictor and had the best predictive ability for abnormal FEV1/FVC (area under the ROC curve 0.732 [95% CI 0.57-0.90], optimal cutoff 17 Hz, 87% sensitivity, 62% specificity) and abnormal forced expiratory flow during the middle half of the FVC maneuver (area under the ROC curve 0.667 [95% CI 0.53-0.81], optimal cutoff 15 Hz, 77% sensitivity, 54% specificity). Area of reactance and the difference in respiratory resistance at 5 Hz and 20 Hz also showed a good predictive ability for abnormal FEV1/FVC (area under the ROC curve 0.716 and 0.730, respectively). CONCLUSIONS: We found that the IOS performed well in diagnosing small airway and obstructive diseases among hospitalized subjects. IOS might serve as an alternative to standard PFTs in non-cooperative or dyspneic hospitalized patients.
- Subjects
LUNG physiology; OBSTRUCTIVE lung disease diagnosis; PULMONARY function tests; STATISTICAL correlation; CONTINUING education units; RECEIVER operating characteristic curves; BODY mass index; VITAL capacity (Respiration); HOSPITAL care; FUNCTIONAL assessment; PILOT projects; AGE distribution; DESCRIPTIVE statistics; TERTIARY care; LONGITUDINAL method; RESEARCH; FORCED expiratory volume; COMPARATIVE studies; CONFIDENCE intervals; HEALTH facilities; DATA analysis software; SENSITIVITY &; specificity (Statistics); OBESITY
- Publication
Respiratory Care, 2024, Vol 69, Issue 4, p415
- ISSN
0020-1324
- Publication type
Article
- DOI
10.4187/respcare.10963