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- Title
Repurposing QuantiFERON for Detection of Neutralizing Interferon-γ Autoantibodies in Patients With Nontuberculous Mycobacterial Infections.
- Authors
Suárez, Isabelle; Lehmann, Clara; Gruell, Henning; Graeb, Jessica; Kochanek, Matthias; Fätkenheuer, Gerd; Plum, Georg; van Wengen, Annelies; van de Vosse, Esther; Hartmann, Pia; Hanitsch, Leif G.; Rybniker, Jan
- Abstract
Nontuberculous mycobacterial infections due to autoantibodies targeting interferon-γ are an emerging medical problem. However, case finding is hampered due to highly complex diagnostic procedures not available in routine laboratories. We show that QuantiFERON assays can be exploited as a simple screening tool that may facilitate adequate and timely treatment.
- Subjects
MYCOBACTERIAL disease treatment; MYCOBACTERIAL diseases; INTERFERONS; AUTOANTIBODIES; MEDICAL care; PATIENTS
- Publication
Clinical Infectious Diseases, 2017, Vol 65, Issue 3, p518
- ISSN
1058-4838
- Publication type
Article
- DOI
10.1093/cid/cix372