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- Title
Male infertility treatment for cancer survivors: does anticancer treatment affect infertility treatment?
- Authors
Hatsuki Hibi; Miho Sugie; Tadashi Ohori; Noritaka Fukunaga; Megumi Sonohara; Yoshimasa Asada
- Abstract
We investigated the impact of prior anticancer treatments such as chemotherapy and radiotherapy on subsequent infertility treatment in cancer survivors who consulted our male infertility division. Of 1,525 male infertility patients who consulted our division between 2008 and 2018, 56 (3.7%) were cancer survivors. Of these, 32 received anticancer treatment (group A) and 24 were treated with surgery alone or were seen before anticancer treatment (group B). Semen analysis revealed that azoospermia in 26 subjects (81.3%) and 14 (58.3%) in groups A and B respectively. Ejaculatory dysfunction was observed 1 in group A and in 2 group B subjects. Sperm cryopreservation before anticancer treatment was performed 4 subjects. Sperm retrieval surgery for intracytoplasmic sperm injection (ICSI) was performed in 13 cases in group A and 10 in group B. Motile sperm were recovered in 7 subjects and in 8 subjects in group A and B respectively. Overall pregnancies and deliveries with ICSI were achieved for 7 subjects (21.9%) in group A, and 9 (37.5%) in group B. Successful sperm retrieval may not be affected by prior anticancer treatment as shown in this study. However, some patients abandoned infertility treatment due to the cost of testing and sperm retrieval surgery. Support for the cost of infertility treatment in cancer survivors is necessary.
- Subjects
INFERTILITY treatment; CANCER survivors; PREMATURE ejaculation; INTRACYTOPLASMIC sperm injection; FROZEN semen
- Publication
Nagoya Journal of Medical Science, 2020, Vol 82, Issue 4, p677
- ISSN
0027-7622
- Publication type
Article
- DOI
10.18999/nagjms.82.4.677