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- Title
Machine Learning Approach to Support the Detection of Parkinson's Disease in IMU-Based Gait Analysis.
- Authors
Trabassi, Dante; Serrao, Mariano; Varrecchia, Tiwana; Ranavolo, Alberto; Coppola, Gianluca; De Icco, Roberto; Tassorelli, Cristina; Castiglia, Stefano Filippo
- Abstract
The aim of this study was to determine which supervised machine learning (ML) algorithm can most accurately classify people with Parkinson's disease (pwPD) from speed-matched healthy subjects (HS) based on a selected minimum set of IMU-derived gait features. Twenty-two gait features were extrapolated from the trunk acceleration patterns of 81 pwPD and 80 HS, including spatiotemporal, pelvic kinematics, and acceleration-derived gait stability indexes. After a three-level feature selection procedure, seven gait features were considered for implementing five ML algorithms: support vector machine (SVM), artificial neural network, decision trees (DT), random forest (RF), and K-nearest neighbors. Accuracy, precision, recall, and F1 score were calculated. SVM, DT, and RF showed the best classification performances, with prediction accuracy higher than 80% on the test set. The conceptual model of approaching ML that we proposed could reduce the risk of overrepresenting multicollinear gait features in the model, reducing the risk of overfitting in the test performances while fostering the explainability of the results.
- Subjects
PARKINSON'S disease; ARTIFICIAL neural networks; GAIT in humans; SUPPORT vector machines; FEATURE selection; MACHINE learning; TREADMILLS
- Publication
Sensors (14248220), 2022, Vol 22, Issue 10, p3700
- ISSN
1424-8220
- Publication type
Article
- DOI
10.3390/s22103700