We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Recording of Ictal Epileptic Activity Using on‐Scalp Magnetoencephalography.
- Authors
Feys, Odile; Corvilain, Pierre; Van Hecke, Audrey; Sculier, Claudine; Rikir, Estelle; Legros, Benjamin; Gaspard, Nicolas; Leurquin‐Sterk, Gil; Holmes, Niall; Brookes, Matthew; Goldman, Serge; Wens, Vincent; De Tiège, Xavier
- Abstract
The absence of simultaneous OPM-MEG/SEEG recording or comparison with cryogenic MEG (unavailable at the time of recording due to technical issues) prevents proper estimation of OPM-MEG localization accuracy for ictal discharges. In drug-resistant focal epilepsy (DRFE), seizures are infrequent and unpredictable, requiring prolonged recordings to identify the seizure-onset zone (SOZ).[1] Cryogenic magnetoencephalography (MEG) is thus scarcely used for ictal recordings but rather to detect interictal epileptiform discharges (IEDs) and localize the irritative zone (IZ), which may differ from the SOZ.[1] On-scalp MEG based on a new-generation, cryogenic-free magnetic sensors, "optically-pumped magnetometers" (OPM-MEG), allows successful localization of IEDs with higher amplitude and signal-to-noise ratio (SNR) than cryogenic MEG.[2] Although OPM-MEG has clear advantages (i.e., on-scalp recording, increase in SNR, free head movements[3]) over cryogenic MEG to record ictal discharges, no study has demonstrated the ability of OPM-MEG to detect ictal discharges. We report on a 10-year-old boy suffering from DRFE (>5 seizures/day) who underwent on-scalp ictal and interictal video-OPM-MEG recording at rest (1 hour) and during hyperventilation as a seizure activation procedure (3 minutes).
- Subjects
MAGNETOENCEPHALOGRAPHY; PEOPLE with epilepsy; EPILEPSY; HYPERVENTILATION; EPILEPTIFORM discharges; PARIETAL lobe; SCHOOL children; TEMPORAL lobectomy
- Publication
Annals of Neurology, 2023, Vol 93, Issue 2, p419
- ISSN
0364-5134
- Publication type
Article
- DOI
10.1002/ana.26562