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- Title
(Pro)renin Receptor: A Treatment Target for Diabetic Retinopathy?
- Authors
Wilkinson-Berka, Jennifer L.; Campbell, Duncan J.
- Abstract
The authors comment on a study by S. Satofuka et al. on the role of prorenin and the (pro)renin receptor in the pathogenesis of diabetic retinopathy published within the issue. At issue is whether the actions of (pro)renin receptor blockers (PRRB) serve a role for prorenin and the (pro)renin receptor in diabetic retinopathy. Another issue deals with the adequacy of the concentrations of PRRB in vivo in the prevention of prorenin binding to the (pro)renin receptor.
- Subjects
RENIN; DIABETIC retinopathy; DIABETES complications; RETINAL diseases; PROTEIN binding
- Publication
Diabetes, 2009, Vol 58, Issue 7, p1485
- ISSN
0012-1797
- Publication type
Opinion
- DOI
10.2337/db09-0604