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- Title
The Role of the Gut Microbiome in the Development of Acute Pancreatitis.
- Authors
Zhou, Ruilin; Wu, Qingyang; Yang, Zihan; Cai, Yanna; Wang, Duan; Wu, Dong
- Abstract
With the explosion research on the gut microbiome in the recent years, much insight has been accumulated in comprehending the crosstalk between the gut microbiota community and host health. Acute pancreatitis (AP) is one of the gastrointestinal diseases associated with significant morbidity and subsequent mortality. Studies have elucidated that gut microbiota are engaged in the pathological process of AP. Herein, we summarize the major roles of the gut microbiome in the development of AP. We then portray the association between dysbiosis of the gut microbiota and the severity of AP. Finally, we illustrate the promises and challenges that arise when seeking to incorporate the microbiome in acute pancreatitis treatment.
- Subjects
GUT microbiome; PANCREATITIS; MICROBIAL communities; GASTROINTESTINAL diseases; DYSBIOSIS
- Publication
International Journal of Molecular Sciences, 2024, Vol 25, Issue 2, p1159
- ISSN
1661-6596
- Publication type
Article
- DOI
10.3390/ijms25021159