We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Advancement in structure elucidation of natural medium-sized lactones through synthesis and theoretical calculations.
- Authors
Katsuta, Ryo
- Abstract
Medium-sized lactones are an important class of natural products with diverse biological activities. Unlike conventional organic compounds, these molecules exhibit elevated levels of conformational flexibility. This inherent structural feature occasionally exacerbates the complexities associated with determining their conformation, thereby posing challenges in deciphering their stereochemistry or, in certain instances, leading to incorrect structures. This review highlights specific scenarios in which synthetic studies and computational chemistry have assumed pivotal roles in unveiling the structures of lactones, which have previously eluded definitive elucidation.
- Subjects
LACTONES; COMPUTATIONAL chemistry; ORGANIC compounds
- Publication
Bioscience, Biotechnology & Biochemistry, 2024, Vol 88, Issue 3, p260
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1093/bbb/zbad179