We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Limbic-predominant age-related TDP-43 encephalopathy neuropathological change (LATE-NC) is independently associated with dementia and strongly associated with arteriolosclerosis in the oldest-old.
- Authors
Harrison, William T.; Lusk, Jay B.; Liu, Beiyu; Ervin, John F.; Johnson, Kim G.; Green, Cynthia L.; Wang, Shih-Hsiu J.
- Abstract
Our study showed a high prevalence of LATE-NC in the oldest old, consistent with previous large autopsy cohorts; similarly, we observed strong associations between LATE-NC and HS and arteriolosclerosis [[1]]. We performed additional analysis of the association between arteriolosclerosis and LATE-NC by brain region, graded according to previous guidelines [[5]] (Table 5, online resource).
- Subjects
DEMENTIA; BRAIN diseases; CEREBRAL amyloid angiopathy; COGNITION disorders; FRONTAL lobe
- Publication
Acta Neuropathologica, 2021, Vol 142, Issue 5, p917
- ISSN
0001-6322
- Publication type
Article
- DOI
10.1007/s00401-021-02360-w