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- Title
Veno-occlusive disease in a fetus caused by pyrrolizidine alkaloids of food origin.
- Authors
Rasenack, R.; Müller, C.; Kleinschmidt, M.; Rasenack, J.; Wiedenfeld, H.; Müller, C
- Abstract
We report the occurrence of veno-occlusive disease in a preterm neonate who was symptomatic with hepatomegaly and ascites and was delivered by caesarean section for threatening fetal asphyxia and died shortly afterwards. Post mortem examination revealed veno-occlusive disease typical for pyrrolizidine alkaloid poisoning. The content of pyrrolizidine alkaloids in the liver could be confirmed. Analysis of a herbal mixture which was used for cooking in the family revealed high amounts of the respective alkaloids clarifying the source of the poison and the causal relationship.
- Subjects
ASCITES; PYRROLIZIDINES; ALKALOIDS; DISEASES; NEWBORN infants; DIAGNOSIS of fetal diseases; BIOLOGICAL products; FETAL diseases; FOOD; HEPATIC veno-occlusive disease; DIAGNOSIS
- Publication
Fetal Diagnosis & Therapy, 2003, Vol 18, Issue 4, p223
- ISSN
1015-3837
- Publication type
journal article
- DOI
10.1159/000070799