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- Title
Imaging Transcriptomics of the Brain for Schizophrenia.
- Authors
Yue-Wen Gu; Jing-Wen Fan; Hóngyi Zhào; Shu-Wan Zhao; Xiao-Fan Liu; Renqiang Yu; Lei Ren; Xinjiang Wang; Hong Yin; Long-Biao Cui
- Abstract
Schizophrenia is a severe mental disorder with a neurodevelopmental origin. Although schizophrenia results from changes in the brain, the underlying biological mechanisms are unknown. Transcriptomics studies quantitative expression changes or qualitative changes of all genes and isoforms, providing a more meaningful biological insight. Magnetic resonance imaging (MRI) techniques play roles in revealing brain structure and function. We give a narrative focused review on the current transcriptome combined with MRI studies related to schizophrenia and summarize the research methodology and content of these studies to identify the research commonalities as well as the implications for future research, in an attempt to provide new insights into the mechanism, clinical diagnosis, and treatments of schizophrenia.
- Publication
Alpha Psychiatry, 2024, Vol 25, Issue 1, p9
- ISSN
2757-8038
- Publication type
Article
- DOI
10.5152/alphapsychiatry.2024.231369