We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Myxedema madness: psychosis may also happen. a review of symptoms through a case report.
- Authors
Pérez-Lombardo, M.; González Castellary, A.; Gómez Beteta, F. J.; Pemán Rodríguez, J.; Ibáñez Vizoso, J. E.; Villanueva Gallego, M.; Jiménez Cabañas, M.; Rodado León, B.; Montero Hernández, G.; Strada Herrera, G.
- Abstract
Introduction: Psychiatrists must always keep in mind the variety of organic mental disorders. Alterations in thyroid hormones are a common cause of psychiatric symptoms, most of them related to mood disorder. However, psychosis is not as well defined as a part of this disorders. Objectives: The aim of this review is to bring closer to professionals this kind of manifestations, with a clinical example with a wide range of symptoms. Methods: We conducted a review of the scientific literature on Pubmed, following a clinical case registered in our center. The search was focused on symptoms, its relation with blood levels of thyroid hormones and treatment. Results: Thyroid disfunction are common and affect almost 5% of the general population, with a female predominance. After Asher (1949) created the concept of "myxedema madness", number of cases in literature has increased. Etiopathogenesis is still unknown, although several theories are defended. There is no correlation between the degree of thyroid dysfunction and the severity of the psychiatric symptoms manifested. Conclusions: - Organic diseases can cause classic psychotic symptoms: hypothyroidism is one of them. - Etiopathogenesis of psychotic symptoms in hypothyroidism is still unknown. - Correlation was not found between the degree of thyroid dysfunction and the severity of the psychiatric symptoms. - Treatment consist on hormone replacement therapy, although some symptoms can remain in some cases. - Further investigations, as well as systematized reviews, are required to get a better knowledge of cases and get an earlier diagnosis.
- Subjects
NEUROBEHAVIORAL disorders; PSYCHOSES; SYMPTOMS; SCIENTIFIC literature; THYROID hormones
- Publication
European Psychiatry, 2020, Vol 63, pS705
- ISSN
0924-9338
- Publication type
Article