We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Impact of Blood Group Phenotypes on COVID-19 Severity and Mortality in Duhok Province: a Prospective Cross-sectional Study.
- Authors
Rasho, Fatima Jaafar; Merza, Muayad Aghali
- Abstract
Objectives: This study aimed to determine the frequency of blood group types among COVID-19 patients and to investigate its potential association with disease severity and patient outcomes. Methods: This prospective cross-sectional study was conducted from February to July 2022 in three different healthcare facilities in the Duhok region. All confirmed PCR confirmed COVID-19 patients were classified into: mild, moderate, severe, and critical cases. Information on demographic, clinical, and laboratory characteristics were collected using a standardized questionnaire. All patients were subjected to ABO blood grouping. The statistical calculations were performed by JMP Pro 14.3.0. A P value of < 0.05 was considered significant. Results: The study comprised of 404 patients. The age range of the patients varied from 16 to 100 years with a male predominance (204, 50.5%). Out of the total patients, 250 (61.88%) had mild-moderate course, while 154 (38.12%) had severe-critical course. The most frequent blood group was O (164, 41.58%), followed by blood group A (121, 29.95%). There was no significant difference in the distribution of the Rh factor among the studied subjects (P = 0.426). There was a significant increase in disease severity and worse outcome with increasing age (P = <0.0001). Considering blood group types, there were no significant differences between blood group types with COVID-19 severity and patients' outcome. Conclusions: Individuals with blood group O may have a higher risk of contracting COVID-19. Advanced age is a crucial predictor of disease severity and poor outcomes. There were no significant association between blood group types with COVID-19 severity and patients' outcome. However, further research is needed to confirm these findings and determine the underlying mechanisms behind any potential association between blood groups and COVID-19 susceptibility, severity, and outcome.
- Subjects
DIHOK (Iraq); BLOOD grouping &; crossmatching; BLOOD groups; ABO blood group system; RH factor; PHENOTYPES
- Publication
Journal of Contemporary Medical Sciences, 2023, Vol 9, Issue 2, p111
- ISSN
2415-1629
- Publication type
Article
- DOI
10.22317/jcms.v9i2.1333