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- Title
P03-544 - Comorbidity of affective disorders
- Authors
Martín Calvo, M.J.; Fernández Mayo, L.; García del Castillo, I.; Carmona Camacho, R.; Serrano Drozdowskyj, E.; Ovejero García, S.; Baca García, E.
- Abstract
Introduction: The studies about the comorbidity of major depressive disorder (MDD) and bipolar disorder (BD) have increased in the last years. The comorbidity with Axis I psychiatric disorders complicates the diagnosis, prognosis and treatment. Objectives: To analyze the prevalence of affective disorders associated with another Axis I psychiatric disorders to treat correctly from the beginning of the diagnosis and to improve the course of the disorder and the quality of life of these patients Methods: The subjects who participated in the study were diagnosed of bipolar I disorder, bipolar II disorder and MDD, according to DSM-IV-TR criteria. The sample (n = 114) was divided into three groups: MDD (n = 58), BD (n = 31) and a control group of healthy subjects (n = 25). The diagnosis and stability were assessed using the MINI International Neuropsyquiatric Interview and the Hamilton Depression Rating Scale (HDRS). Results: BD had a significantly association with risk of suicide (38%), anxiety disorder (3.3%) and social phobia (12.9%). It was also reported a significant association between MDD and risk of suicide (71%), manic/hypomanic episodes (25.9%), anxiety disorder (37.9%), social phobia (25.9%) and generalized anxiety disorder (37.9%). Conclusions: It is necessary for clinical practice an integrative model which takes into account the comorbidity of affective disorders to improve the response to treatment and the prognosis of these mental disorders
- Subjects
AFFECTIVE disorders; MENTAL health services; COMORBIDITY; BIPOLAR disorder; DISEASE complications; DISEASE prevalence; ANXIETY disorders; MENTAL illness; PSYCHIATRIC rating scales; PROGNOSIS
- Publication
European Psychiatry, 2011, Vol 26, p1714
- ISSN
0924-9338
- Publication type
Abstract
- DOI
10.1016/S0924-9338(11)73418-6