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- Title
SOME NEGATIVE PROGNOSTIC FACTORS OF HEART FAILURE.
- Authors
Năstase-Melicovici, D.; Macarie, C.; Coman, Simona; Tilinca, Mariana
- Abstract
The main objective was to establish some prognostic corelations between echographic evaluation, clinical characteristics and clinical simptomatology (NYHA class) and between exercise capacity (measured by Naughton protocol) and ejection fraction of left ventricol. For these objectives we made a transversal,prospective study, which include two groups of patients with dilatative cardiomiopathy confirmated by echography, with ischemic(confirmed by coronarography who revealed coronarian stenosis and diagnosed with acute myocardial infarction) and nonischemic etiology (without coronary artery disease). As a result of statistical methods we considered that evaluation of the factors presented in our study (age,gender,diabetes mellitus, NYHA class,EF,serum sodium,potassium and hemoglobin, GFR) useful, mandatory, relatively easy to obtain and important to improve therapeutical ways in contrast with the determination of natriuretic peptides, troponines or dosing of neurohormonal markers ( norepinephrine, renin, aldosteron, endotelyn) useful in evaluation of neuroendocrine activation, but less useful in diagnosis or prognosis of each patient. From 9 factors studied we found only 4 to be significant for exercise capacity of patient with heart failure: ejection fraction, hemoglobin, sodium levels and glomerular filtration rate. Decreased renal function and hiponatremia represent powerful negative predictors on mortality, superior to NYHA class.
- Subjects
HEART failure; HEART disease prognosis; CARDIOVASCULAR diseases; CORONARY disease; MYOCARDIAL infarction; CORONARY artery abnormalities; PROGNOSIS
- Publication
Annals of the Romanian Society for Cell Biology, 2012, Vol 17, Issue 2, p101
- ISSN
2067-3019
- Publication type
Article