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- Title
Comparison of the Diagnostic Performance of Multiparametric Prostate Magnetic Resonance Imaging Results with Classical Parameters for Prostate Carcinoma in Gray Zone Patients.
- Authors
Bostancı, Coşkun; Demir, Demirhan Örsan
- Abstract
Objective: To compare the diagnostic value of prostate imaging-reporting and data system (mpMRI) version 2.0 with classical parameters for prostate cancer detection in gray zone patients with ultrasonography-guided prostate biopsy as a reference point. Materials and Methods: With the retrospective nature of the study, 438 biopsy-naïve patients in the gray zone with pre-biopsy mpMRI were reviewed. Ultrasonography-guided transrectal prostate biopsy was the reference point. Diagnostic performance of classical parameters compared with mpMRI results for prostate carcinoma and clinically significant prostate carcinoma. Results: The overall cancer detection rate was 30%. Prostate-specific antigen density, free/total prostate-specific antigen ratio, prostate volume, suspicious digital rectal examination, and mpMRI score >3 were independent predictors of clinically significant prostate carcinoma. Prostatespecific antigen density followed by free/total prostate-specific antigen ratio had the largest area under the curve values compared with mpMRI score >3 for prostate carcinoma and clinically significant prostate carcinoma. Conclusion: Classical parameters, prostate-specific antigen density, and f/t prostate-specific antigen ratio were still critical to deciding prostate biopsy in gray zone patients, in whom ultrasonography-guided transrectal prostate biopsy was used as a reference point. In centers where targeted fusion biopsies were unavailable, pre-biopsy mpMRI still had some benefits. However, biopsy decisions should be made according to each patient's individual characteristics.
- Subjects
BIOPSY; RISK assessment; PROSTATE-specific antigen; EARLY detection of cancer; MAGNETIC resonance imaging; PROSTATE tumors; RETROSPECTIVE studies; DESCRIPTIVE statistics; DIGITAL rectal examination; SENSITIVITY &; specificity (Statistics); DISEASE risk factors
- Publication
Journal of Urological Surgery, 2024, Vol 11, Issue 2, p58
- ISSN
2148-9580
- Publication type
Article
- DOI
10.4274/jus.galenos.2023.2023-6-17