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- Title
Use of Infliximab to Treat Paradoxical Tuberculous Meningitis Reactions.
- Authors
Marais, Ben J; Cheong, Elaine; Fernando, Shelanah; Daniel, Santhosh; Watts, Matthew R; Berglund, Lucinda J; Barry, Simone E; Kotsiou, George; Headley, Alex P; Stapledon, Richard A
- Abstract
We documented dramatic responses to infliximab in 4 tuberculous meningitis cases with severe paradoxical reactions after effective antibacterial treatment, despite high-dose steroids. In every instance, infliximab was used as a last resort after all other options were exhausted, resulting in delayed initiation that may have adversely affected patient outcomes.
- Subjects
INFLIXIMAB; TUBERCULOUS meningitis
- Publication
Open Forum Infectious Diseases, 2021, Vol 8, Issue 1, p1
- ISSN
2328-8957
- Publication type
Article
- DOI
10.1093/ofid/ofaa604