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T-bet<sup>+</sup>CD11c<sup>+</sup> B cells are critical for antichromatin immunoglobulin G production in the development of lupus.
Published in:
Arthritis Research & Therapy, 2017, v. 19, p. 1, doi. 10.1186/s13075-017-1438-2
By:
- Ya Liu;
- Shiyu Zhou;
- Jie Qian;
- Yan Wang;
- Xiang Yu;
- Dai Dai;
- Min Dai;
- Lingling Wu;
- Zhuojun Liao;
- Zhixin Xue;
- Jiehua Wang;
- Goujun Hou;
- Jianyang Ma;
- Harley, John B.;
- Yuanjia Tang;
- Nan Shen
Publication type:
Article
Noncanonical functions of microRNAs in the nucleus.
Published in:
Acta Biochimica et Biophysica Sinica, 2024, v. 56, n. 2, p. 151, doi. 10.3724/abbs.2023268
By:
- Jiayi Gu;
- Yuanan Li;
- Youtong Tian;
- Yehao Zhang;
- Yongjun Cheng;
- Yuanjia Tang
Publication type:
Article
Fibroblast expression of neurotransmitter receptor HTR2A associates with inflammation in rheumatoid arthritis joint.
Published in:
Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01352-w
By:
- Xiang, Chunyan;
- Hong, Soon-Min;
- Zhao, Bingjiao;
- Pi, Hui;
- Du, Fang;
- Lu, Xingyu;
- Tang, Yuanjia;
- Shen, Nan;
- Yang, Chunxi;
- Wang, Runci
Publication type:
Article
SARS-CoV-2-Encoded MiRNAs Inhibit Host Type I Interferon Pathway and Mediate Allelic Differential Expression of Susceptible Gene.
Published in:
Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.767726
By:
- Zhu, Youwei;
- Zhang, Zhaoyang;
- Song, Jia;
- Qian, Weizhou;
- Gu, Xiangqian;
- Yang, Chaoyong;
- Shen, Nan;
- Xue, Feng;
- Tang, Yuanjia
Publication type:
Article
Lupus enhancer risk variant causes dysregulation of IRF8 through cooperative lncRNA and DNA methylation machinery.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-29514-y
By:
- Zhou, Tian;
- Zhu, Xinyi;
- Ye, Zhizhong;
- Wang, Yong-Fei;
- Yao, Chao;
- Xu, Ning;
- Zhou, Mi;
- Ma, Jianyang;
- Qin, Yuting;
- Shen, Yiwei;
- Tang, Yuanjia;
- Yin, Zhihua;
- Xu, Hong;
- Zhang, Yutong;
- Zang, Xiaoli;
- Ding, Huihua;
- Yang, Wanling;
- Guo, Ya;
- Harley, John B.;
- Namjou, Bahram
Publication type:
Article
The microRNA miR-23b suppresses IL-17-associated autoimmune inflammation by targeting TAB2, TAB3 and IKK-?
Published in:
Nature Medicine, 2012, v. 18, n. 7, p. 1077, doi. 10.1038/nm.2815
By:
- Zhu, Shu;
- Pan, Wen;
- Song, Xinyang;
- Liu, Yan;
- Shao, Xinrui;
- Tang, Yuanjia;
- Liang, Dong;
- He, Dongyi;
- Wang, Honglin;
- Liu, Wenjun;
- Shi, Yufang;
- Harley, John B;
- Shen, Nan;
- Qian, Youcun
Publication type:
Article
MiR-125a Is a critical modulator for neutrophil development.
Published in:
PLoS Genetics, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pgen.1007027
By:
- Qin, Yuting;
- Wu, Lingling;
- Ouyang, Ye;
- Zhou, Ping;
- Zhou, Haibo;
- Wang, Yan;
- Ma, Jianyang;
- Zhang, Jinsong;
- Chen, Yanan;
- Qian, Jie;
- Tang, Yuanjia;
- Shen, Nan
Publication type:
Article
miR-152 Attenuates the Severity of Lupus Nephritis Through the Downregulation of Macrophage Migration Inhibitory Factor (MIF)-Induced Expression of COL1A1.
Published in:
Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00158
By:
- Zheng, Jiayi;
- Guo, Ruru;
- Tang, Yuanjia;
- Fu, Qiong;
- Chen, Jie;
- Wu, Lingling;
- Leng, Lin;
- Bucala, Richard;
- Song, Yang;
- Lu, Liangjing
Publication type:
Article
A Novel Vector-Based Method for Exclusive Overexpression of Star-Form MicroRNAs.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0041504
By:
- Bo Qu;
- Xiao Han;
- Yuanjia Tang;
- Nan Shen
Publication type:
Article
Enhanced transfection of polyplexes based on pluronic-polypropylenimine dendrimer for gene transfer.
Published in:
Archives of Pharmacal Research, 2009, v. 32, n. 7, p. 1045, doi. 10.1007/s12272-009-1710-3
By:
- Hao, Junguo;
- Sha, Xianyi;
- Tang, Yuanjia;
- Jiang, Ye;
- Zhang, Zhiwen;
- Zhang, Wei;
- Li, Yajuan;
- Fang, Xiaoling
Publication type:
Article
Anti-Toxoplasma gondii antibodies as a risk factor for the prevalence and severity of systemic lupus erythematosus.
Published in:
Parasites & Vectors, 2024, v. 17, n. 1, p. 1, doi. 10.1186/s13071-024-06141-8
By:
- Li, Zhongzhen;
- Lei, Zhiwei;
- Yang, Wanying;
- Jing, Chunxia;
- Sun, Xiaolin;
- Yang, Guang;
- Zhao, Xiaozhen;
- Zhang, Mingjiao;
- Xu, Miaomiao;
- Tang, Yuanjia;
- Wang, Qingwen;
- Zhao, Jing;
- Zhou, Zixing;
- Wen, Zihao;
- Chen, Xiaojing;
- Peng, Qinglin;
- Wang, Guochun;
- Zhang, Pingjing;
- Sun, Erwei;
- Shen, Nan
Publication type:
Article
Serum Metabolic Fingerprints Characterize Systemic Lupus Erythematosus.
Published in:
Advanced Science, 2024, v. 11, n. 2, p. 1, doi. 10.1002/advs.202304610
By:
- Li, Shunxiang;
- Ding, Huihua;
- Qi, Ziheng;
- Yang, Jing;
- Huang, Jingyi;
- Huang, Lin;
- Zhang, Mengji;
- Tang, Yuanjia;
- Shen, Nan;
- Qian, Kun;
- Guo, Qiang;
- Wan, Jingjing
Publication type:
Article
Zirconia Hybrid Nanoshells for Nutrient and Toxin Detection.
Published in:
Small, 2020, v. 16, n. 46, p. 1, doi. 10.1002/smll.202003902
By:
- Rana, Md Sohel;
- Xu, Lin;
- Cai, Jingyi;
- Vedarethinam, Vadanasundari;
- Tang, Yuanjia;
- Guo, Qiang;
- Huang, Hongtao;
- Shen, Nan;
- Di, Wen;
- Ding, Huihua;
- Huang, Lin;
- Qian, Kun
Publication type:
Article
Association of large intergenic noncoding RNA expression with disease activity and organ damage in systemic lupus erythematosus.
Published in:
Arthritis Research & Therapy, 2015, v. 17, n. 1, p. 1, doi. 10.1186/s13075-015-0632-3
By:
- Yanfang Wu;
- Feifei Zhang;
- Jianyang Ma;
- Xiaoyan Zhang;
- Lingling Wu;
- Bo Qu;
- Shiwei Xia;
- Shunle Chen;
- Yuanjia Tang;
- Nan Shen
Publication type:
Article
MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis.
Published in:
Nature Communications, 2015, v. 6, n. 5, p. 7096, doi. 10.1038/ncomms8096
By:
- Pan, Wen;
- Zhu, Shu;
- Dai, Dai;
- Liu, Zheng;
- Li, Dan;
- Li, Bin;
- Gagliani, Nicola;
- Zheng, Yunjiang;
- Tang, Yuanjia;
- Weirauch, Matthew T.;
- Chen, Xiaoting;
- Zhu, Wei;
- Wang, Yue;
- Chen, Bo;
- Qian, Youcun;
- Chen, Yingxuan;
- Fang, Jingyuan;
- Herbst, Ronald;
- Richman, Laura;
- Jallal, Bahija
Publication type:
Article
Prevalence of Neutralizing Autoantibodies Against Type I Interferon in a Multicenter Cohort of Severe or Critical COVID-19 Cases in Shanghai.
Published in:
Journal of Clinical Immunology, 2024, v. 44, n. 3, p. 1, doi. 10.1007/s10875-024-01683-z
By:
- Shi, Dongling;
- Chen, Jie;
- Zhao, Meng;
- Tang, Yuanjia;
- Zhao, Chen;
- Jin, Yinpeng;
- Tian, Di;
- Liao, Yixin;
- Wang, Xuebi;
- Wang, Wei;
- Fan, Xiaohong;
- Yi, Zhigang;
- Chen, Xiaohua;
- Ling, Yun
Publication type:
Article
Genetic polymorphism in the 3′-untranslated region of the E-cadherin gene is associated with risk of different cancers.
Published in:
Molecular Carcinogenesis, 2011, v. 50, n. 11, p. 857, doi. 10.1002/mc.20765
By:
- Li, Yan;
- Tang, Yuanjia;
- Zhou, Rongmiao;
- Sun, Donglan;
- Duan, Yanan;
- Wang, Na;
- Chen, Zhifeng;
- Shen, Nan
Publication type:
Article
MicroRNA-130b Ameliorates Murine Lupus Nephritis Through Targeting the Type I Interferon Pathway on Renal Mesangial Cells.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 9, p. 2232, doi. 10.1002/art.39725
By:
- Han, Xiao;
- Wang, Yan;
- Zhang, Xiaoyan;
- Qin, Yuting;
- Qu, Bo;
- Wu, Lingling;
- Ma, Jianyang;
- Zhou, Zhenyuan;
- Qian, Jie;
- Dai, Min;
- Tang, Yuanjia;
- Chan, Edward K. L.;
- Harley, John B.;
- Zhou, Shiyu;
- Shen, Nan
Publication type:
Article
Identification of Cyclin-Dependent Kinase 1 as a Novel Regulator of Type I Interferon Signaling in Systemic Lupus Erythematosus.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 5, p. 1222, doi. 10.1002/art.39543
By:
- Wu, Lingling;
- Qin, Yuting;
- Xia, Shiwei;
- Dai, Min;
- Han, Xiao;
- Wu, Yanfang;
- Zhang, Xiaoyan;
- Ma, Jianyang;
- Wang, Yan;
- Tang, Yuanjia;
- Liu, Zheng;
- Zhu, Wei;
- Jallal, Bahija;
- Yao, Yihong;
- Qu, Bo;
- Shen, Nan
Publication type:
Article
In Vivo Therapeutic Success of MicroRNA-155 Antagomir in a Mouse Model of Lupus Alveolar Hemorrhage.
Published in:
Arthritis & Rheumatology, 2016, v. 68, n. 4, p. 953, doi. 10.1002/art.39485
By:
- Zhou, Shiyu;
- Wang, Yan;
- Meng, Yao;
- Xiao, Chunyuan;
- Liu, Zheng;
- Brohawn, Philip;
- Higgs, Brandon W.;
- Jallal, Bahija;
- Jia, Qian;
- Qu, Bo;
- Huang, Xinfang;
- Tang, Yuanjia;
- Yao, Yihong;
- Harley, John B.;
- Shen, Nan
Publication type:
Article
Type I Interferon Inhibition of MicroRNA-146a Maturation Through Up-Regulation of Monocyte Chemotactic Protein-Induced Protein 1 in Systemic Lupus Erythematosus.
Published in:
Arthritis & Rheumatology, 2015, v. 67, n. 12, p. 3209, doi. 10.1002/art.39398
By:
- Qu, Bo;
- Cao, Jianchang;
- Zhang, Feifei;
- Cui, Huijuan;
- Teng, Jialin;
- Li, Jia;
- Liu, Zheng;
- Morehouse, Chris;
- Jallal, Bahija;
- Tang, Yuanjia;
- Guo, Qiang;
- Yao, Yihong;
- Shen, Nan
Publication type:
Article
miR-744 enhances type I interferon signaling pathway by targeting PTP1B in primary human renal mesangial cells.
Published in:
Scientific Reports, 2015, p. 12987, doi. 10.1038/srep12987
By:
- Zhang, Xiaoyan;
- Han, Xiao;
- Tang, Yuanjia;
- Wu, Yanfang;
- Qu, Bo;
- Shen, Nan
Publication type:
Article
MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways.
Published in:
Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0068-3
By:
- Cai, Zongye;
- Li, Jian;
- Zhuang, Qi;
- Zhang, Xueming;
- Yuan, Ancai;
- Shen, Lan;
- Kang, Kang;
- Qu, Bo;
- Tang, Yuanjia;
- Pu, Jun;
- Gou, Deming;
- Shen, Jieyan
Publication type:
Article
MiR-125a-5p ameliorates monocrotaline-induced pulmonary arterial hypertension by targeting the TGF-β1 and IL-6/STAT3 signaling pathways.
Published in:
Experimental & Molecular Medicine EMM, 2018, v. 50, n. 4, p. 1, doi. 10.1038/s12276-018-0068-3
By:
- Cai, Zongye;
- Li, Jian;
- Zhuang, Qi;
- Zhang, Xueming;
- Yuan, Ancai;
- Shen, Lan;
- Kang, Kang;
- Qu, Bo;
- Tang, Yuanjia;
- Pu, Jun;
- Gou, Deming;
- Shen, Jieyan
Publication type:
Article
A Functional Variant in MicroRNA-146a Promoter Modulates Its Expression and Confers Disease Risk for Systemic Lupus Erythematosus.
Published in:
PLoS Genetics, 2011, v. 7, n. 6, p. 1, doi. 10.1371/journal.pgen.1002128
By:
- Xiaobing Luo;
- Wanling Yang;
- Dong-Qing Ye;
- Huijuan Cui;
- Yan Zhang;
- Nattiya Hirankarn;
- Xiaoxia Qian;
- Yuanjia Tang;
- Yu Lung Lau;
- De Vries, Niek;
- Tak, Paul Peter;
- Tsao, Betty P.;
- Nan Shen
Publication type:
Article
Interferon-α exacerbates neuropsychiatric phenotypes in lupus-prone mice.
Published in:
Arthritis Research & Therapy, 2019, v. 21, n. 1, p. N.PAG, doi. 10.1186/s13075-019-1985-9
By:
- Zeng, Jing;
- Meng, Xinyu;
- Zhou, Ping;
- Yin, Zhihua;
- Xie, Qinglian;
- Zou, Hong;
- Shen, Nan;
- Ye, Zhizhong;
- Tang, Yuanjia
Publication type:
Article
Three‐Dimensional Chromosomal Landscape Revealing miR‐146a Dysfunctional Enhancer in Lupus and Establishing a CRISPR‐Mediated Approach to Inhibit the Interferon Pathway.
Published in:
Arthritis & Rheumatology, 2024, v. 76, n. 3, p. 384, doi. 10.1002/art.42703
By:
- Zhu, Xinyi;
- Zhang, Yutong;
- Yin, Zihang;
- Ye, Zhizhong;
- Qin, Yuting;
- Cheng, Zhaorui;
- Shen, Yiwei;
- Yin, Zhihua;
- Ma, Jianyang;
- Tang, Yuanjia;
- Ding, Huihua;
- Guo, Ya;
- Hou, Guojun;
- Shen, Nan
Publication type:
Article
Integrative Functional Genomics Identifies Systemic Lupus Erythematosus Causal Genetic Variant in the IRF5 Risk Locus.
Published in:
Arthritis & Rheumatology, 2023, v. 75, n. 4, p. 574, doi. 10.1002/art.42390
By:
- Hou, Guojun;
- Zhou, Tian;
- Xu, Ning;
- Yin, Zhihua;
- Zhu, Xinyi;
- Zhang, Yutong;
- Cui, Yange;
- Ma, Jianyang;
- Tang, Yuanjia;
- Cheng, Zhaorui;
- Shen, Yiwei;
- Chen, Yashuo;
- Zou, Ling‐Hua;
- Wang, Yong‐fei;
- Yin, Zihang;
- Guo, Ya;
- Ding, Huihua;
- Ye, Zhizhong;
- Shen, Nan
Publication type:
Article
SLE non-coding genetic risk variant determines the epigenetic dysfunction of an immune cell specific enhancer that controls disease-critical microRNA expression.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-020-20460-1
By:
- Hou, Guojun;
- Harley, Isaac T. W.;
- Lu, Xiaoming;
- Zhou, Tian;
- Xu, Ning;
- Yao, Chao;
- Qin, Yuting;
- Ouyang, Ye;
- Ma, Jianyang;
- Zhu, Xinyi;
- Yu, Xiang;
- Xu, Hong;
- Dai, Dai;
- Ding, Huihua;
- Yin, Zhihua;
- Ye, Zhizhong;
- Deng, Jun;
- Zhou, Mi;
- Tang, Yuanjia;
- Namjou, Bahram
Publication type:
Article

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