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- Title
Is there a role for endothelin antagonists in diabetic renal disease?
- Authors
Jandeleit-Dahm, Karin; Allen, Terri J.; Youssef, Sherif; Gilbert, Richard E.; Cooper, Mark E.
- Abstract
Evaluates the role for endothelin (ET) antagonists in diabetic renal disease. Specificities and potencies in inhibiting ET receptor mediated effects; Importance of blood pressure reduction in retarding the progression of diabetic nephropathy; Effects of selective and non-selective ET antagonists and angiotensin converting enzymes inhibitors on growth factor expression in experimental diabetes.
- Subjects
ENDOTHELINS; DIABETES; KIDNEY diseases; ANGIOTENSIN converting enzyme; CHEMICAL inhibitors
- Publication
Diabetes, Obesity & Metabolism, 2000, Vol 2, Issue 1, p15
- ISSN
1462-8902
- Publication type
Article
- DOI
10.1046/j.1463-1326.2000.00045.x