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- Title
The influence of two different dental local anaesthetic solutions on the haemodynamic responses of children undergoing restorative dentistry: a randomised, single-blind, split-mouth study.
- Authors
Meechan, J.G.; Cole, B.; Welbury, R.R.
- Abstract
<bold>Objectives: </bold>This investigation was designed to study the haemodynamic effects of two different local anaesthetic solutions during restorative dental treatment in children.<bold>Design: </bold>A randomised, single-blind, split-mouth cross-over design was employed using children undergoing bilaterally similar restorative treatments over two visits.<bold>Setting: </bold>The study was performed in a dental hospital paediatric dentistry department.<bold>Methods: </bold>Ten children participated. At one visit the local anaesthetic was 2% lidocaine (lignocaine) with 1:80,000 epinephrine (adrenaline); at the other the anaesthetic was 3% prilocaine with 0.03IU/ml felypressin. Local anaesthetic was administered at a dose of 0.5 ml/10 kg body weight. Blood pressure and heart rate were measured before and during treatment with an automatic blood pressure recorder. Data were analysed by ANOVA and Student's paired t test.<bold>Results: </bold>Significant differences between treatments in diastolic blood pressure (F = 2.37; P = 0.05) and heart rate (F = 2.98; P< 0.02) were noted. The heart rate increased ten minutes following the injection of the epinephrine-containing solution. The diastolic blood pressure fell 20 minutes after injection of lidocaine with epinephrine.<bold>Conclusion: </bold>The choice of local anaesthetic solution influences the haemodynamic response during restorative treatment in children.
- Subjects
DENTAL anesthesia; OPERATIVE dentistry; HEMODYNAMICS; CHILDREN'S dental care; ADRENALINE; ANALYSIS of variance; BLOOD pressure; CLINICAL trials; COMPARATIVE studies; DENTAL fillings; HEART beat; LIDOCAINE; LOCAL anesthetics; RESEARCH methodology; MEDICAL cooperation; RESEARCH; VASOCONSTRICTORS; VASOPRESSIN; EVALUATION research; RANDOMIZED controlled trials; BLIND experiment; PHARMACODYNAMICS
- Publication
British Dental Journal, 2001, Vol 190, Issue 9, p502
- ISSN
0007-0610
- Publication type
journal article
- DOI
10.1038/sj.bdj.4801015