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- Title
Starch/rhodamine 6G conjugate as a non-cytotoxic, effective, and selective fluorescent chemosensor for detection of Fe<sup>3+</sup> ion.
- Authors
Alavifar, Seyyed-Mahdi; Golshan, Marzieh; Hosseini, Mahdi Salami; Salami-Kalajahi, Mehdi
- Abstract
Iron is a crucial trace mineral vital for maintaining optimal human health and well-being. Despite being needed in small amounts, its importance cannot be overstated as it plays an important role in various physiological processes. In this research, we have developed a fluorescence probe utilizing starch functionalized with derivatives of rhodamine 6G to efficiently detect Fe3+ ions. This structure forms selfassembled starch/rhodamine 6G (RS0) fluorescent nanoparticles that exhibit strong fluorescence intensity under ultraviolet light. The ability of Fe3+ ions to increase the fluorescence of the RS0 probe enables the effective detection of Fe3+ ions. Importantly, this fluorescence increasing effect is specific to Fe3+ ions and remains unaffected by the presence of other metal ions. MTT assay against SH-SY5Y cells showed that RS0 was rather cytocompatible. Finally, SH-SY5Y cells were used to measure cell uptake and fluorescence imaging performances of RS0 which showed a good ability for live-cell fluorescence imaging.
- Subjects
CHEMORECEPTORS; RHODAMINE B; STARCH; METAL ions; IONS; ULTRAVIOLET radiation; CORNSTARCH
- Publication
Polymers from Renewable Resources, 2024, Vol 15, Issue 2, p181
- ISSN
2041-2479
- Publication type
Article
- DOI
10.1177/20412479241230934