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- Title
Carcinosarcoma of pancreas with liver metastasis combined with gastrointestinal stromal tumour of the stomach: is there a good prognosis with the complete resection?
- Authors
Z. L. SHEN; S. WANG; Y. J. YE; Y. L. WANG; K. K. SUN; X. D. YANG; K. W. JIANG
- Abstract
SHEN Z.L., WANG S., YE Y.J., WANG Y.L., SUN K.K., YANG X.D. & JIANG K.W. (2009) European Journal of Cancer Care 19, 118–123 Carcinosarcoma of pancreas with liver metastasis combined with gastrointestinal stromal tumour of the stomach: is there a good prognosis with the complete resection? We report a carcinosarcoma of the pancreas with liver metastasis combined with gastrointestinal stromal tumour (GIST) of the stomach in a 72-year-old woman who presented with right upper quadrant pain, nausea and vomiting. A radical resection including pancreaticoduodenectomy, left hepatic lobe resection and local resection of the gastric mass was performed. The tumour in the head of pancreas was found to be grossly yellow-white, and it infiltrated the common bile duct and duodenum; the mass of the liver metastasis is solitary. Pathologic examination showed two components separated from each other: one component was a conventional infiltrating pancreatic ductal adenocarcinoma, and the other component showed sarcomatous growth pattern composed of pleomorphic spindle cells. The neoplasm of the stomach was confirmed a low malignant potential GIST by histology and immunohistochemistry. The patient was obliged to be in hospital because of abnormal bowel function; moreover, surveillance CT scans performed at 1.5 months post-operatively showed multiple liver metastasis and recurrence in the tail of pancreas. Unfortunately, the patient died of multiple organ failure at 2 months post-operatively. To our knowledge, this is the first experience report about surgical treatment of carcinosarcoma of pancreas with liver metastasis combined with GIST of the stomach. The patient performed a radical surgery for the metastatic carcinosarcoma even if that could be resected completely did not have a good consequence.
- Subjects
PANCREATIC cancer; LIVER metastasis; GASTROINTESTINAL stromal tumors; NAUSEA; PAIN; VOMITING; ADENOCARCINOMA; SARCOMA
- Publication
European Journal of Cancer Care, 2010, Vol 19, Issue 1, p118
- ISSN
0961-5423
- Publication type
Article
- DOI
10.1111/j.1365-2354.2008.00977.x