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- Title
Identification of a novel ITGAX::RN7SL2 fusion in acute myelocytic leukemia.
- Authors
Su, Zhan; Cong, Beibei; Li, Xiaojuan
- Abstract
The article presents a case study of a 55-year-old female diagnosed with myelodysplastic syndromes (MDS) progressing to acute myelocytic leukemia (AML), revealing a novel fusion gene detected through transcriptome sequencing. Topics discussed include the clinical history of the patient, molecular characterization of the fusion gene, and the potential implications of non-coding Ribonucleic Acid (RNA) involvement in leukemia pathogenesis.
- Subjects
ANEMIA diagnosis; PROTEINS; PHYSICAL diagnosis; LYMPH nodes; BONE marrow examination; MYELODYSPLASTIC syndromes; ERYTHROCYTES; FATIGUE (Physiology); HEADACHE; CHROMOSOME abnormalities; DNA; GENES; RNA; GENE expression; KARYOTYPES; CYTOPLASM; GENE expression profiling; SEQUENCE analysis
- Publication
International Journal of Laboratory Hematology, 2024, Vol 46, Issue 3, p577
- ISSN
1751-5521
- Publication type
Case Study
- DOI
10.1111/ijlh.14263