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- Title
Clinicopathologic study of thyroid carcinoma infiltrating the trachea.
- Authors
Tsumori, Takao; Nakao, Kazuyasu; Miyata, Masahiko; Izukura, Masaaki; Monden, Yasumasa; Sakurai, Masami; Kawashima, Yasunaru; Nakahara, Kazuya; Tsumori, T; Nakao, K; Miyata, M; Izukura, M; Monden, Y; Sakurai, M; Kawashima, Y; Nakahara, K
- Abstract
Eighteen patients (10 women and 8 men), ranging in age from 37 to 80 years, with thyroid carcinoma infiltrating the trachea comprised this series. Eleven had primary and 7 had recurrent cases. Total laryngectomy was performed in 4 patients, and tracheal resection was carried out followed by end-to-end anastomosis in 13 patients. In one patient, reconstruction was done with Naville's artificial trachea after tracheal resection. Eleven patients were alive after 1 year and 8 months to 6 years and 7 months after the operation. This result was significantly better than that of a group of ten patients without resection of the infiltrated trachea (seven patients died within 6 months). Thus, combined resection of the upper airway improved the prognosis of advanced thyroid carcinoma with tracheal infiltration. Histologic examination of surgical specimens demonstrated well-differentiated carcinoma in seven patients, poorly differentiated carcinoma in seven patients, undifferentiated carcinoma in three patients, and squamous cell carcinoma in one patient. The result showed a higher frequency of poorly differentiated carcinoma than in the control group of 70 patients without tracheal infiltration.
- Subjects
TRACHEAL surgery; ADENOCARCINOMA; CANCER invasiveness; LARYNGECTOMY; PROGNOSIS; RESPIRATORY organ tumors; THYROID gland tumors
- Publication
Cancer (0008543X), 1985, Vol 56, Issue 12, p2843
- ISSN
0008-543X
- Publication type
journal article
- DOI
10.1002/1097-0142(19851215)56:12<2843::AID-CNCR2820561221>3.0.CO;2-Q