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- Title
Exercise training modifies gut microbiota in normal and diabetic mice.
- Authors
Lambert, Jennifer E.; Myslicki, Jason P.; Bomhof, Marc R.; Belke, Darrell D.; Shearer, Jane; Reimer, Raylene A.
- Abstract
Cecal microbiota from type 2 diabetic ( db/db) and control ( db/ +) mice was obtained following 6 weeks of sedentary or exercise activity. qPCR analysis revealed a main effect of exercise, with greater abundance of select Firmicutes species and lower Bacteroides/Prevotella spp. in both normal and diabetic exercised mice compared with sedentary counterparts. Conversely, Bifidobacterium spp. was greater in exercised normal but not diabetic mice (exercise × diabetes interaction). How exercise influences gut microbiota requires further investigation.
- Subjects
GUT microbiome; ANALYSIS of covariance; ANALYSIS of variance; ANIMAL experimentation; BACTERIA; DIABETES; EXERCISE; MICE; RESEARCH funding; DATA analysis software; DESCRIPTIVE statistics
- Publication
Applied Physiology, Nutrition & Metabolism, 2015, Vol 40, Issue 7, p749
- ISSN
1715-5312
- Publication type
Article
- DOI
10.1139/apnm-2014-0452