We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Sero-positive blood donors to Trypanosoma cruzi: focus on the diagnostic.
- Authors
Novaes, Rômulo Dias; Gonçalves, Reggiani Vilela
- Abstract
We read with great interest and in detail the study by González-Guzmán et al.[1] The authors, by employing an extensive serologic screening over 6.5 years, investigated serum samples of 510,047 blood donors and reported the prevalence of I Trypanosoma cruzi i infection in an endemic area for Chagas disease. Accordingly, in the case of discordant results, immunoblotting with I T. cruzi i antigens or polymerase chain reaction (PCR) methods are recommended to distinguish infections by different pathogens.[[3]] Based on the fact that serologic methods fails to detect 1.6% to 2.5% of cases of infection,[[2], [4]] we believe that the use of molecular methods may expand the mapping of I T. cruzi i infection prevalence in endemic and nonendemic areas.
- Subjects
BLOOD donors; TRYPANOSOMA cruzi; CHAGAS' disease
- Publication
Transfusion, 2019, Vol 59, Issue 9, p3031
- ISSN
0041-1132
- Publication type
letter
- DOI
10.1111/trf.15391