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- Title
Facial nerve ganglioneuroblastoma in a feline leukemia virus-positive cat.
- Authors
Reis Pereira, Paula; Tagliari Junior, Nelson; Leite-Filho, Ronaldo Viana; da Cruz Schaefer, Gabriela; Amorim da Costa, Fernanda Vieira; Petinatti Pavarini, Saulo
- Abstract
Neuroblastic tumors can originate from the central neuraxis, olfactory epithelium, adrenal medullary region or autonomous system. Ganglioneuroblastoma are a type of neuroblastic tumor, with very few case descriptions in animals. Diagnosis of facial nerve ganglioneuroblastoma was made in a feline leukemia virus-positive 11-month-old cat. The cat had hyporexia, left head tilt, depressed mental state, horizontal nystagmus, inability to retract the pinched left lip, anisocoria, ptosis, and absence of the menace reflex. Gross necropsy showed a mass at the left facial nerve root region. Histological examination of this mass showed neoplastic proliferation of neuroblasts arranged in a cohesive pattern and mature ganglion cells. Ganglion cells were positive for neurofilament, neuron-specific enolase, S100, and glial fibrillary acidic protein by immunohistochemistry, while neuroblasts were positive for vimentin, S100, neuron-specific enolase and feline leukemia virus.
- Subjects
NEUROBLASTOMA; TUMORS; OLFACTORY nerve; EPITHELIUM; CAT diseases
- Publication
Ciência Rural, 2017, Vol 47, Issue 5, p1
- ISSN
0103-8478
- Publication type
Article
- DOI
10.1590/0103-8478cr20160675