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- Title
Effect of ICSI on Subsequent Blastocyst Development and Pregnancy Rates.
- Authors
Westphal, Lynn M.; Hinckley, Mary D.; Behr, Barry; Milki, Amin A.
- Abstract
Purpose: To investigate whether ICSI (intracytoplasmic sperm injection) results in decreased blastocyst formation and pregnancy compared to IVF (in vitro fertilization). Methods: We performed a retrospective analysis of blastocyst transfer (BT) offered routinely to patients under age 40 with ≥ three 8-cell embryos on day 3 and compared IVF to ICSI cycles. Sequential media were used with P1 until day 3, then Blastocyst Medium until day 5/6. Results: There were 131 IVF and 75 ICSI cycles. There was no difference in age, number of oocytes, zygotes, 8-cell embryos, blastocysts on days 5 and 6, or embryos transferred. Progression to blastocyst was similar (78% for IVF and 73% for ICSI) as was the viable pregnancy rate (51.4% for IVF and 55% for ICSI). No cycles failed to form blastocysts. Conclusions: The progression to blastocyst and the likelihood of conceiving a viable pregnancy were unaltered by ICSI. Thus it seems appropriate for programs to offer BT to patients undergoing ICSI using the same inclusion criteria applied to their IVF patients.
- Subjects
BLASTOCYST; FERTILIZATION in vitro
- Publication
Journal of Assisted Reproduction & Genetics, 2003, Vol 20, Issue 3, p113
- ISSN
1058-0468
- Publication type
Article
- DOI
10.1023/A:1022678807398