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- Title
Structural determination of an A-glycan moiety attached to the prothoracicotropic hormone from the silkmoth Bombyx mori.
- Authors
Shinji Nagata; Jun Kobayashi; Hiroshi Kataoka; Akinori Suzuki
- Abstract
The article focuses on a study that investigated the structure of an N-glycan moiety attached to the prothoracicotropic hormone (PTTH) from the silkmoth Bombyx (B.) mori. The researchers conducted an ecdysis progression assay which indicated that N-glycosylated PTTH showed a slightly higher activity compared to the recombinant PTTH without N-glycosylation produced by an Escherichia coli expression system. They concluded that N-glycosylation reinforces the biological activity of PTTH.
- Subjects
GLYCAN structure; PROTHORACICOTROPIC hormones; SILKWORMS; GLYCOSYLATION; MOIETIES (Chemistry); ESCHERICHIA coli
- Publication
Bioscience, Biotechnology & Biochemistry, 2014, Vol 78, Issue 8, p1381
- ISSN
0916-8451
- Publication type
Article
- DOI
10.1080/09168451.2014.925777