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- Title
The obstetrical consequences of ischemic stroke in women of childbearing age.
- Authors
David, Jeremy; Desmurs-Clavel, Helene; Mechtouff, Laura; Long, Anne; Dargaud, Yesim; Catella, Judith
- Abstract
Purpose: Although recurrence risk is a major concern for women having had an ischemic stroke (IS) and who are planning a pregnancy, studies on recurrence risk and pregnancy outcomes are scarce and heterogeneous. Methods: This retrospective study assessed women aged 15–44 years with a diagnosis of ischemic stroke admitted in the Lyon Stroke Centre, France, between January 2009 and December 2013. The primary outcome was stroke recurrence during pregnancy or the post-partum period. Secondary outcomes were pregnancy complications. Results: Overall, 104 women with a prior ischemic stroke were included. Mean age at the time of the stroke was 36 ± 6.7 years old. Stroke etiology was large-artery atherosclerosis for 1 woman, cardioembolism for 23 women, and undetermined for 55 women. No antiphospholipid syndrome was found. Among them, 29 women had 58 subsequent pregnancies. Overall, there were three IS recurrence (2.9%), but none occurred during pregnancy. There were 27 miscarriages (47% of pregnancies), two pre-eclampsia (3%), and one stillbirth (1.7%). Conclusions: We observed no recurrence of IS during pregnancy. The study also highlighted that the risk of miscarriages was higher than general population and that of stillbirth should be further studied.
- Subjects
FRANCE; ISCHEMIC stroke; CHILDBEARING age; PREGNANCY complications; PREGNANCY outcomes; STROKE
- Publication
Archives of Gynecology & Obstetrics, 2024, Vol 310, Issue 1, p405
- ISSN
0932-0067
- Publication type
Article
- DOI
10.1007/s00404-024-07498-y