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- Title
Synthesis of steroid hormones highly labeled with tritium and their use for assessing the activity of aromatase.
- Authors
Shevchenko, V. P.; Nagaev, I. Yu.; Shevchenko, K. V.; Myasoedov, N. F.; Bochkareva, N. V.; Kolomiets, L. A.; Kondakova, I. V.
- Abstract
Steroids highly labeled with tritium (progesterone, estradiol, androstenedione) were synthesized and used to assess the activity of aromatase at various pathologies. The high activity of aromatase in endometrium in endometrium cancer patients without myoma corresponds to a worse prognosis.
- Subjects
STEROIDS; TRITIUM; AROMATASE; ENDOMETRIAL cancer; CYCLOPENTAPHENANTHRENE; MUSCLE tumors
- Publication
Radiochemistry, 2004, Vol 46, Issue 5, p494
- ISSN
1066-3622
- Publication type
Article
- DOI
10.1007/s11137-005-0018-5