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- Title
Oxygen Sensing: Physiology and Pathophysiology.
- Authors
Aaronson, Philip I.; Rocher, Asuncion
- Abstract
Thus, the concentrations of H SB 2 sb S and O SB 2 sb in cells vary inversely, such that, for example, CB Type 1 cell H SB 2 sb S release and CB-induced activity of the sinus nerve show a very similar dependence on pO SB 2 sb over the range relevant to physiological hypoxia [[7]]. Oxygen is such an essential element for life that multiple mechanisms have evolved to maintain oxygen homeostasis, including those which detect decreases in arterial O SB 2 sb and generate adaptive responses to hypoxia. The carotid body (CB) is the main peripheral chemoreceptor that orchestrates the body's homeostatic response to hypoxia. In mammals, oxygen sensing mechanisms are found in erythropoietin-producing cells, peripheral chemoreceptor cells (carotid and aortic bodies), pulmonary artery smooth muscle cells, pulmonary neuroepithelial cells, chromaffin cells, and some specific types of neurons.
- Subjects
X chromosome; WEIGHT loss; ADIPOSE tissue physiology; ENDOTHELIN receptors; PATHOLOGICAL physiology; BIOPRINTING; PHYSIOLOGY
- Publication
Antioxidants, 2022, Vol 11, Issue 5, p1018
- ISSN
2076-3921
- Publication type
Editorial
- DOI
10.3390/antiox11051018