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- Title
EFFECT OF INFLUENZA VACCINATION ON SEASONAL MORTALITY.
- Authors
Petra, IŠTOKOVIČOVÁ; Tomáš, SZALAY; Zuzana, KRIŠTÚFKOVÁ; Veronika, RYBANSKÁ; Andrea, KOLOŠOVÁ; Slávka, LITVOVÁ; Nina, KOTLEBOVÁ
- Abstract
Introduction: Seasonal influenza is one of the acute respiratory infections caused by influenza viruses. In addition to acute respiratory disease, it also causes complications of a patient's preexisting conditions with possible fatal consequences. The aim: To verify whether influenza vaccination has an effect on reducing seasonal mortality. Methods: We conducted a Case-control Study. We used the administrative data of the health insurance company Dôvera (1.6 milion insured persons). We monitored the vaccination coverage of all Dôvera clients, vaccination coverage by gender, and separately for persons 60 years of age and older. We compared the all-cause mortality in the group of those vaccinated against influenza with the all-cause mortality in the group of non-vaccinated. We created the group of unvaccinated by randomly pairing 1:1 with the vaccinated based on age, sex, and the most expensive diagnosis. We analyzed 5 influenza seasons - 2017/18, 2018/19, 2019/20, 2020/21 and 2021/22 (September - April). We excluded the 2020/21 influenza season from the mortality analysis, due to the increased mortality from COVID-19. Results: The vaccination coverage rate of persons aged 60 and older was from 6.6 % in the 60 - 64-years-age group in the 2019/20 season to 23.8 % in the 80 - 84-years age group in the 2018/19 season. There were no significant differences between the vaccination coverage rates of men and women. All-cause mortality in the unvaccinated group was in the range 2.02 - 2.29 % in analysed seasons, in the vaccinated group 1.31 - 1.47 %, OR = 1.45 - 1.7. Significant differences were found in older age groups, in people over 60 years, OR = 1.47 - 1.74. Results were statistically non-significant in the group under 60 years old. Conclusion: We consider influenza vaccination to be a suitable tool for reducing the seasonal mortality.
- Subjects
SEASONAL influenza; INFLUENZA vaccines; RESPIRATORY infections; MORTALITY; HEALTH insurance
- Publication
Zdravotnicke listy, 2023, Vol 11, Issue 4, p6
- ISSN
1339-3022
- Publication type
Article