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- Title
Clinical Utility of Vitamin D3 As Potent Biomarker in Cardiovascular and Liver Disorders.
- Authors
Rana, Aparamita; Singh, Ankita; Sharma, Narotam; Kamboj, Kanika; Kumar, Vivek; Soni, Ashish
- Abstract
Vitamin D is lipophilic substance needed for calcium and phosphate balance and the regulation of the osteo-metabolic system. The purpose of the study was to look at the possible significance of Vitamin D3 as a biomarker for liver enzymes and cholesterol. 249 cases were analysed, with different combinations of liver enzymes, vitamin D3, and cholesterol. 75 clinical samples were processed over the course of the 3 year study. 46(61.3%) were females and 29 (38.6%) were males. Males were more affected than females. In respect to Vitamin D3, the age group of 41-60 years had a large range of cholesterol levels and liver enzyme values. 11% of cases had high SGOT levels, while 13% had aberrant cholesterol values. Above the age of 60, there was a linear connection between cholesterol and liver enzymes. There was seasonal variations in serum 25-OHD levels. Winter (November-March) indicated a Vitamin D3 deficiency in the blood serum, accounting for 74 cases (66%). Autumn and summer had the best range, with only 0 and 16 cases (14.2%), respectively. Despite wide variability in serum vitamin D levels, the differences were not statistically significant. Vitamin D3 can be an important biomarker in clinical practice since it can aid in the early detection of potential hazards linked with cardiovascular disease and liver dysfunction.
- Subjects
CHOLECALCIFEROL; CARDIOVASCULAR diseases; LIVER enzymes; VITAMIN D; BIOMARKERS
- Publication
Journal of Advanced Zoology, 2023, Vol 44, p168
- ISSN
0253-7214
- Publication type
Article