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- Title
Medicamente care cresc riscul fotosensibilizării.
- Authors
Pogonea, Ina; Chiriac, Tatiana; MihalachiAnghel, Maria; Latus, Svetlana
- Abstract
Photosensitization, occurring as a result of drug treatment, represents 8% of all drug-induced skin adverse reactions. The drug photosensitization reaction is unpredictable and every patient can be affected, as it can occur at any age and can be caused by numerous drugs. Currently, two types of photosensitization reactions are known, namely: phototoxic and photoallergic reactions. Phototoxicity reactions are manifested by a direct action of cellular destruction, are not immune-mediated, are dose-dependent, and can occur at first exposure in most individuals receiving photosensitizing drugs. Photoallergic reactions are immune-mediated, not dose-dependent, occur only in sensitized individuals, and are characterized by cross-reactions between related compounds. There are a lot of photosensitizing drugs such as: antibiotics, sulfanilamides, fluoroquinolones, nonsteroidal anti-inflammatory drugs, diuretics, hormonal contraceptives, retinoids, etc. Some drugs cause only one type of reaction, while others may cause both. In general, the prognosis of drug photosensitization reactions is a good one, if certain rules are followed, such as the use of protective creams, clothing and protective glasses together with the drugs, as well as the doctor’s supervision of the treatment evolution.
- Publication
Farmacist.ro, 2024, Vol 216, Issue 1, p26
- ISSN
1584-6539
- Publication type
Article