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- Title
A rare case of brucine poisoning complicated by rhabdomyolysi and acute renal failure.
- Authors
Naik, B. Sadananda; Chakrapani, M.
- Abstract
Brucine is the predominant alkaloid present in the bark of the tree Strychnos flux vomica and is a weaker alkaloid when compared to strychnine. However, its toxicological property is akin to strychnine. We report a rare case of brucine poisoning complicated by acute renal failure and rhabdomyolysis. A 24-year-old male presented with a history of consumption of a decoction made from the bark of the Strychnos flux vomica tree. Soon after, he developed widespread muscle spasms and convulsions, which were promptly treated. On the fifth day of admission, he developed features of rhabdomyolysis and acute renal failure. Investigations revealed elevated creatine phosphokinase levels and elevated blood urea and serum creatinine. The patient was managed with hemodialysis and recovered gradually. There are many reports of strychnine poisoning producing rhabdomyolysis and renal failure. In this case report, attention is drawn to the fact that brucine, although a weaker alkaloid, can also produce life threatening complications like rhabdomyolysis and acute renal failure.
- Subjects
RHABDOMYOLYSIS; ACUTE kidney failure; SPASMS; HEMODIALYSIS; STRYCHNOS; KIDNEY diseases
- Publication
Malaysian Journal of Pathology, 2009, Vol 31, Issue 1, p67
- ISSN
0126-8635
- Publication type
Article