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- Title
Hypoglossal nerve stimulation in the treatment of obstructive sleep apnea in down syndrome patients: A systematic review and meta-analysis.
- Authors
ALABDALLAT, Yasmeen Jamal; ALSALHI, Hamza K.; MOSA, Benyameen Y.; HAWAS, Yousef; ELBORAAY, Toka; ALKHAWALDEH, Ibraheem M.; JARADAT, Jaber H.; ABUNAR, Obada Ahmad; ABDALLAH, Adam M.; KAMAL, Zaid
- Abstract
Obstructive sleep apnea (OSA) is highly prevalent in individuals with Down syndrome (DS), affecting more than 50% of this population during childhood and reaching up to 100% in adulthood. This disorder poses significant clinical consequences, including impaired cognitive function, developmental delay, and cardiovascular complications. To address this, direct hypoglossal nerve stimulation (HNS) has been approved as a treatment modality for OSA. Recent studies have shown a significant positive correlation between HNS voltage and post-apnea-hypopnea index (AHI) levels in DS and non-DS patients. However, concerns regarding the reliability of some findings have been raised, emphasizing the need for further research to underline the usefulness of HNS in treating OSA in DS patients. This meta-analysis provides a comprehensive review and analysis of the available case reports, case series, and cohort studies to evaluate the safety and efficacy of HNS in treating OSA in Down syndrome patients.
- Subjects
HYPOGLOSSAL nerve; PEOPLE with Down syndrome; SLEEP apnea syndromes; NEURAL stimulation; DOWN syndrome
- Publication
Journal of Experimental & Clinical Medicine / Deneysel ve Klinik Tip Dergisi, 2024, Vol 41, Issue 2, p407
- ISSN
1309-4483
- Publication type
Article
- DOI
10.52142/omujecm.41.2.30