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- Title
Improving diabetes outcomes through lifestyle change - A randomized controlled trial.
- Authors
Delahanty, Linda M.; Dalton, Kristen M.; Porneala, Bianca; Chang, Yuchiao; Goldman, Valerie M.; Levy, Douglas; Nathan, David M.; Wexler, Deborah J.
- Abstract
Objective To compare a diabetes group lifestyle intervention (GLI) with dietitian referral for medical nutrition therapy (RD) for weight loss in the usual care setting. Methods Randomized clinical trial was conducted with 57 primary care patients with type 2 diabetes and body mass index (BMI) >25 kg/m2 who received either a dietitian-led 19-week GLI adapted from the Look AHEAD study or RD. Outcome measures include 6-month and 1-year weight loss, changes in medications, glycemic control, cardiac risk factors, and cost analysis. Results Patients were mean age 61, 59% male, and 32% non-white, and they weighed 97 kg with mean HbA1c 8.2%. At 6 months, 46% of GLI vs. 21% of RD lost ≥5% body weight ( P = 0.04), with mean weight loss 6.6 (SD 7.0) kg with GLI and 2.1 (3.5) kg in RD ( P = 0.004). HbA1c improved by 0.70 (1.13) vs. 0.39 (1.51) in GLI vs. RD ( P = 0.4), respectively, and 82% vs. 38% stopped or reduced diabetes medications ( P < 0.001). Weight loss remained significantly greater in GLI compared to RD at 1 year. GLI program cost was $578 per participant. Conclusions An affordable GLI achieved significantly more weight loss and medication reduction than RD in primary care patients with type 2 diabetes.
- Subjects
TREATMENT of diabetes; CARBOHYDRATE intolerance; ENDOCRINE diseases; LIFESTYLES; RANDOMIZED controlled trials
- Publication
Obesity (19307381), 2015, Vol 23, Issue 9, p1792
- ISSN
1930-7381
- Publication type
Article
- DOI
10.1002/oby.21172