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- Title
Combined Papillary Renal Cell Carcinoma with Neuroendocrine Differentiation and Mucinous Tubular and Spindle Cell Carcinoma.
- Authors
Wang, Gang; Yuan, Ren; Tucker, Tracy; Gates, Allan B.; Bellamy, Christopher D.; Hayes, Malcolm M.
- Abstract
A unique case of combined papillary renal cell carcinoma (PRCC) and mucinous tubular and spindle cell carcinoma (MTSCC) presenting in a man aged 67 years is reported. The two separate components were distinct on morphological, immunohistochemical (IHC), and genetic grounds, while type 2 PRCC predominated. Three years after the initial diagnosis, the PRCC component metastasized to the lungs where it morphologically mimicked a pulmonary neuroendocrine tumor. Retrospectively focal neuroendocrine differentiation was demonstrated by IHC in the PRCC component of the primary neoplasm.
- Subjects
RENAL cell carcinoma; SQUAMOUS cell carcinoma; NEUROENDOCRINE tumors; IMMUNOSTAINING; NEPHRECTOMY
- Publication
Case Reports in Pathology, 2018, p1
- ISSN
2090-6781
- Publication type
Article
- DOI
10.1155/2018/8734823