We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Haematological Changes in Donors Post Apheresis.
- Authors
NIKHIL; DAS, SUBHASHISH; SNIGDHA
- Abstract
Introduction: The productivity, quality of platelet apheresis collection has improved because of the considerable advancement in the automated cell separators. Automated cell separators have lot of sizeable scientific advances, but the alertness has been centered to Platelet Concentrates (PCs) quality than on safety of donor. Aim: To find the changes in haematological parameters and also finds the consequences of apheresis and plateletpheresis on donor's health. Materials and Methods: It is observational cross-sectional study done in laboratory at RL Jalappa Blood Bank, Tamaka, Kolar, Karnataka, India. The study was done from March 2019 to August 2020. A total of 300 healthy donors (plateletpheresis donors) are involved in the study. The plateletpheresis (Haemonetics MCS), pre donation and postdonation haematological parameters such as haemoglobin concentration, Haematocrit (Hct), platelet, white and red blood cell count were calculated in all donors. The samples for Complete Blood Count (CBC) were secured from the donors, at the beginning and end of the procedure. Postdonation haematological parameters such as platelet count, haemoglobin, haematocrit, White Blood Cells (WBC), Red Blood Cells (RBC) counts of the donor was inscribed and comparison done with the pre donation haematological parameters. Quality control of all Single Donor Platelet (SDP) products was done. All donors were evaluated for adverse donor reactions. The mean preand post plateletpheresis values comparison was done utilising paired t-test. Statistical analysis was accomplished utilising statistical software Statistical Package for the Social Sciences (SPSS) version 16.0. Results: Platelet count, haemoglobin, WBC count, RBC count and haematocrit were jotted down from 263 donors and a significant decrease was noticed in these parameters in the postdonation. Donor parameter platelet count (lac/ml) value was decreased from 273.57 to 224.28 whereas WBC count (cu/mm) pre donation value decreased from 9.91 to 8.86 Postdonation, haemoglobin (g/dL) value decreased from 14.46 to 12.91, haematocrit (%) decreased slightly from 45.19 to 44.19, RBC count (million/mm3) decreased from 5.21 to 5.01. This concluded that the values decreased postdonation. Conclusion: The study conducted was safe from donor's point of view. SDP is very effective in treatment of thrombocytopenia and is safe from recipient's point of view.
- Subjects
SPSS (Computer software); BLOOD cell count; LEUCOCYTES; ERYTHROCYTES; LEUKOCYTE count; PLATELET count
- Publication
Journal of Clinical & Diagnostic Research, 2021, Vol 15, Issue 7, p39
- ISSN
0973-709X
- Publication type
Article
- DOI
10.7860/JCDR/2021/48896.15157