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- Title
Carcinosarcoma with choriocarcinomatous and osteosarcomatous differentiation in a patient with juvenile polyposis syndrome.
- Authors
Parra-Medina, Rafael; López Correa, Patricia; Jiménez Moreno, Julian; Moreno Lucero, Paula; Yaspe, Edgardo; Polo, Fernando
- Abstract
Juvenile polyposis syndrome (JPS) is an infrequent autosomal dominant hereditary predisposition to the occurrence of hamar-tomatous polyps in the colon and rectum. We describe the case of a 12-year-old boy with JPS associated with an abdominal tumor. Histological sections of the abdominal tumor showed components of adenocarcinoma, osteosarcoma, and choriocarcinoma. Immunohistochemistry was AE1/AE3, CK7, HCG and SALL4 positive. Juvenile polyposis syndrome patients are at increased risk of colorectal adenocarcinoma. However, we present a case of an adenocarcinoma associated with other unusual components. This association has not been reported before.
- Subjects
CARCINOSARCOMAS; JUVENILE polyposis syndrome; GENETIC disorders; PATIENTS
- Publication
Rare Tumors, 2015, Vol 7, Issue 3, p117
- ISSN
2036-3605
- Publication type
Case Study
- DOI
10.4081/rt.2015.5778