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- Title
Effect of photofunctionalization on titanium bone-implant integration in ovariectomized rats.
- Authors
Shuhei KEMURIYAMA; Hideki AITA; Takeo MAIDA; Naohiko KAWAMURA; Takashi NEZU; Masahiro IIJIMA; Kazuhiko ENDO; Hisashi KOSHINO
- Abstract
Osteoporosis is considered a risk factor for osseointegration during implant treatment. Photofunctionalization of titanium has been shown to improve bone-based cell adhesion, proliferation, and functional expression, increasing the bone-implant contact rate and bone-implant integration strength. This study aimed to test the hypothesis that photofunctionalization is effective for implant fixation using an osteoporosis rat model. In the biomechanical push-in test, the bone-implant integration strength of the photofunctionalization treatment group was 1.53 times that of the control group (p<0.05). These values implied that photofunctionalization restored the ovariectomy-induced low bone-implant integration strength to normal states. In the micro-CT analysis, the BV/TV of the photofunctionalization treatment group was 1.32 times that of the control group (p<0.05). These values implied that photofunctionalization restored the ovariectomy-induced low peri-implant bone formation to normal states. These results indicate that photofunctionalization treatment increased peri-implant bone formation and bone-implant integration strength in ovariectomized rats.
- Subjects
TITANIUM; X-ray computed microtomography; BONE growth; CELL adhesion; RATS
- Publication
Dental Materials Journal, 2023, Vol 42, Issue 1, p11
- ISSN
0287-4547
- Publication type
Article
- DOI
10.4012/dmj.2022-081