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- Title
Reduced pigmentation (rp), a new coat colour gene with effects on kidney lysosomal glycosidases in the mouse.
- Authors
Gibb, S.; Håkansson, E. M.; Lundin, L.-G.; Shire, J. G. M.
- Abstract
A spontaneous autosomal mutation in C57BL/Tb mice, provisionally called reduced pigmentation, symbol rp, has pronounced effects on three kidney lysosomal glycosidase activities. Homozygous rprp mice have significantly higher activities of β-galactosidase, β-glucuronidase and N-acetyl-β-hexosaminidase than their heterozygous litter-mates. Homozygotes have light ears and tails, diluted fur and dark eyes. The mutation is not allelic to any known to affect lysosomal functions, or to a number of pigmentation variants with similar phenotypic effects. The locus is on chromosome 7.
- Publication
Genetics Research, 1981, Vol 37, Issue 1, p95
- ISSN
0016-6723
- Publication type
Article
- DOI
10.1017/S0016672300020048