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- Title
Glutamyl-γ-methyl ester acts as a methionine analogue in Escherichia coli: analogue resistant mutants map at the metJ and metK loci.
- Authors
Kraus, Jan; Soll, Dieter; Brooks Low, K.
- Abstract
Escherichia coli K-12 mutants resistant to glutamyl-γ-methyl ester were isolated. A mutation leading to resistance of up to 1·4 mg/ml of the methionine analogue maps at min 63 and is 13% cotransducible with serA indicating an alteration in the metK gene. Another mutation leading to resistance to 3 mg/ml of the analogue and cross-resistance to other amino acid analogues maps at min 87. This mutation, which has the phenotype of MetJ−, is shown to be situated between the glpK and metB genes and thus indicates a different gene order from the published one.
- Publication
Genetics Research, 1979, Vol 33, Issue 1, p49
- ISSN
0016-6723
- Publication type
Article
- DOI
10.1017/S0016672300018152