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- Title
Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis.
- Authors
ZHI-HUA LIU; CHAO LI; XING-WEI ZHANG; LIANG KANG; JIAN-PING WANG
- Abstract
Appendicectomy has been the gold standard treatment of acute appendicitis for more than a century, while nonoperative therapies, including antibiotics, have acquired increased interest in recent years. The present meta-analysis aimed to compare the therapeutic effects of antibiotics versus appendicectomy for the treatment of acute appendicitis. Medline, Embase and The Cochrane Library databases were searched. Prospective randomized controlled trials that compared antibiotic treatment with surgery were included. The outcomes evaluated included the time of hospital stay, complications and time to work. There were no statistically significant differences between the antibiotic and appendicectomy groups with regard to the time of hospital stay and complications. However, the time to work was significantly longer in the appendicectomy group when compared with the antibiotic group. In addition, the therapeutic effects of antibiotics and appendicectomy were comparable for the treatment of acute appendicitis.
- Subjects
META-analysis; ANTIBIOTICS; APPENDICITIS; ANTIBIOSIS; GOLD standard
- Publication
Experimental & Therapeutic Medicine, 2014, Vol 7, Issue 5, p1181
- ISSN
1792-0981
- Publication type
Article
- DOI
10.3892/etm.2014.1584